Comments on: Working Memory And Some Really Disturbing Disorders http://onebrainsjourney.com/working-memory-and-some-really-disturbing-disorders This is about my journey to understanding how my brain works Mon, 14 Jun 2010 17:46:27 -0400 http://wordpress.org/?v=2.9.2 hourly 1 By: JanetK http://onebrainsjourney.com/working-memory-and-some-really-disturbing-disorders/comment-page-1#comment-11 JanetK Tue, 26 Jan 2010 09:56:09 +0000 http://onebrainsjourney.com/?p=200#comment-11 It seems to me that the fetal development of the brain is more complicated then the development of the limbs or the gut etc. But the brain construction would be similar to limb construction in that it would be controlled but a group of developmental signaling chemicals. I may be quite wrong of course and I haven't any firm evidence to support the brain's program being more complex. It could be that just because we cannot see the damage with our eyes (as with limbs), it seems more complex. But, if we look at what thalidamide did to the development of limbs, it is clear that the same chemical interference with development can product a variety of results depending on the dose and timing. I am dyslexic but my brother had a different problem (probably a just functioning autism spectrum problem). I assume that the two conditions have a similar genetic cause that acted through a disruption of signals during brain development and that left some connections missing or faulty. In effect, this would be the same/similar fault with a different environment/timing that resulted in a different apparent condition. It could be that schizophrenia and OCD are very similar in cause but different in severity, triggers, timing etc. leading to an apparently different condition. It seems to me that the fetal development of the brain is more complicated then the development of the limbs or the gut etc. But the brain construction would be similar to limb construction in that it would be controlled but a group of developmental signaling chemicals. I may be quite wrong of course and I haven’t any firm evidence to support the brain’s program being more complex. It could be that just because we cannot see the damage with our eyes (as with limbs), it seems more complex.

But, if we look at what thalidamide did to the development of limbs, it is clear that the same chemical interference with development can product a variety of results depending on the dose and timing. I am dyslexic but my brother had a different problem (probably a just functioning autism spectrum problem). I assume that the two conditions have a similar genetic cause that acted through a disruption of signals during brain development and that left some connections missing or faulty. In effect, this would be the same/similar fault with a different environment/timing that resulted in a different apparent condition.

It could be that schizophrenia and OCD are very similar in cause but different in severity, triggers, timing etc. leading to an apparently different condition.

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